THE INFLUENCE OF VANADIUM SALTS ON DIABETOGENESIS PROCESS IN BB RAT
DIRECTOR of the PROJECT
ALLOCATED VALUE (USD)
CHETA DAN MIRCEA
100000
Description of the project: "THE PROJECT'S GOAL WAS TO ASSESS THE VANADIUM'S CAPACITY TO PREVENT THE ONSET OF DIABETES MELLITUS IN BB (BIO BREEDING) RATS - AN ANIMAL MODEL IN WHICH A SPONTANEOUS TYPE 1 DIABETES, VERY SIMILAR WITH THE HUMAN DISEASE, DEVELOPS) AND IT'S POSSIBLE TOXIC EFFECTS, BASED ON DOSAGE AND RATE OF ADMINISTRATION. THUS, WE ACHIEVED A DELAY IN THE CLINICAL ONSET OF DIABETES AND, IN CASE DIABETES OCCURRED, OUR TARGET WAS TO OBTAIN A HYPOGLYCEMIC EFFECT FOR A LONG PERIOD OF TIME, AFTER THE CESSATION OF ADMINISTRATION, AT THE OPTIMAL DOSES THAT PREVENTED VANADIUM'S TOXIC EFFECTS."
